Graphiti MCP vs OMOP MCP Server

A side-by-side comparison of two AI, Data & Knowledge servers — tools, transport, auth, maintenance, and copy-paste config for each.

	Graphiti MCP Temporal knowledge-graph memory for agents: add episodes and search facts over FalkorDB or Neo4j, from Zep. Unverified HTTP (remote) API key Python	OMOP MCP Server Map clinical terminology to standardized OMOP CDM concepts using LLMs and the OMOPHub vocabulary API. Unverified stdio (local) API key Python
Category	AI, Data & Knowledge	AI, Data & Knowledge
Language	Python	Python
Transport	HTTP (remote)	stdio (local)
Auth	API key	API key
GitHub stars	28k	36
Last commit	1 month ago	3 months ago
Verified
Actively maintained
Install	`git clone https://github.com/getzep/graphiti.git && cd graphiti/mcp_server && docker compose up`	`git clone https://github.com/OHNLP/omop_mcp.git`
Repo	Open	Open

Verdict

Pick Graphiti MCP if you want the official, vendor-maintained server, and you prefer the more popular, battle-tested option.

Pick OMOP MCP Server if you want a local (stdio) server that keeps data on your machine.

Add Graphiti MCP

Install / run

git clone https://github.com/getzep/graphiti.git && cd graphiti/mcp_server && docker compose up

Paste into ~/Library/Application Support/Claude/claude_desktop_config.json

{
  "mcpServers": {
    "graphiti-mcp": {
      "command": "npx",
      "args": [
        "-y",
        "mcp-remote",
        "http://localhost:8000/mcp/"
      ]
    }
  }
}

Claude Desktop connects to remote servers through the `mcp-remote` proxy (installed on first run via npx). Restart Claude Desktop after saving.

Add OMOP MCP Server

Install / run

git clone https://github.com/OHNLP/omop_mcp.git

Paste into ~/Library/Application Support/Claude/claude_desktop_config.json

{
  "mcpServers": {
    "omop-mcp-server": {
      "command": "uv",
      "args": [
        "--directory",
        "<path-to-local-repo>",
        "run",
        "omop_mcp"
      ]
    }
  }
}

FAQ

Graphiti MCP or OMOP MCP Server — which is better?

Pick Graphiti MCP if you want the official, vendor-maintained server, and you prefer the more popular, battle-tested option. Pick OMOP MCP Server if you want a local (stdio) server that keeps data on your machine.

Can I use both Graphiti MCP and OMOP MCP Server?

Yes — MCP clients let you enable multiple servers at once. Add both configs to your client's mcpServers and use whichever tool fits the task.

Do Graphiti MCP and OMOP MCP Server work with Claude, Cursor and Windsurf?

Both do. Copy the per-client config below into Claude Desktop, Cursor, or Windsurf.

View Graphiti MCP →View OMOP MCP Server →More comparisons →